Stress-enhanced fear learning in rats is resistant to the effects of immediate massed extinction
نویسندگان
چکیده
منابع مشابه
Recent fear is resistant to extinction.
In some individuals, fearful experiences (e.g., combat) yield persistent and debilitating psychological disturbances, including posttraumatic stress disorder (PTSD). Early intervention (e.g., debriefing) after psychological trauma is widely practiced and argued to be an effective strategy for limiting subsequent psychopathology, although there has been considerable debate on this point. Here we...
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Introduction:This study examined the effects of administration of subcutaneous β-estradiol on PTSD-like symptoms (the enhanced conditioned fear response, CFR) that induced by a single-prolonged stress (SPS) and shock in rats. Adult male Wistar rats were exposed to SPS procedure: restraint for 2 h, forced swim for 20 min, and ether anesthesia. Then the rats were placed in fear conditioning syste...
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ژورنال
عنوان ژورنال: Stress
سال: 2012
ISSN: 1025-3890,1607-8888
DOI: 10.3109/10253890.2011.650251